Organ support & nutrition

Association of blood viscosity and device-free days among hospitalized patients with COVID-19

J Intensive CarePublished Retrospective cohort study

Main finding · Respiratory organ support-free days, per 1 centipoise increase in eHSBVResult — go to the resultAdjusted odds ratio 0.68 95% CI 0.59–0.79

Authors' conclusion

Among hospitalized patients with COVID-19, elevated eHSBV and eLSBV at presentation were associated with an increased need for respiratory organ support at 21 days.

Study context

Population
Hospitalized COVID-19 patients diagnosed within 48 h of admission, Mount Sinai Health System, New York City, February 27, 2020 to November 20, 20215,621 in main analysis
Participants
9,278 patients
Exposure
Quartiles of estimated high-shear blood viscosity (eHSBV) and estimated low-shear blood viscosity (eLSBV)
Outcome
Ordinal scale of days free of respiratory organ support (in-hospital death = −1)
Follow-up
Day 21

Main finding

As reported in the abstract

Respiratory organ support-free days, per 1 centipoise increase in eHSBV

Adjusted odds ratio

0.68

95% CI 0.59–0.79

P < 0.001

Per 1 centipoise increase in eHSBV
aOR 0.68 (95% CI 0.59–0.79); P < 0.001

Per 1 centipoise increase in eHSBV, as printed

Observational data: associations, not effects.

Original publication

Association of blood viscosity and device-free days among hospitalized patients with COVID-19. J Intensive Care. Published 2 May 2023. doi:10.1186/s40560-023-00665-4

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