Perioperative medicine & outcomes
Association of body mass index and computed tomography-derived body composition with postoperative cardiovascular events: a secondary analysis of two prospective cohorts
Primary result · Postoperative cardiovascular eventsResult — go to the resultAdjusted odds ratio 0.59 95% CI 0.40–0.88Authors' conclusion
Lower BMI was associated with higher postoperative cardiovascular risk, with heterogeneity by surgical type. When preoperative CT is available, CT-derived body composition phenotyping may provide complementary information beyond BMI, although added predictive value appears modest.
Study context
- Population
- Patients aged ≥45 yr undergoing major noncardiac surgeryCT sub-cohort 2399
- Participants
- 6,320 patients
- Comparison
- BMI and CT-derived body composition phenotypes
- Primary endpoint
- Postoperative cardiovascular events
Methodological detailsmultivariable logistic regression, restricted cubic splines, k-means clustering
- Multivariable logistic regression
- Restricted cubic splines
- K-means clustering
Primary result
As reported in the abstract
Adjusted odds ratio
0.59
95% CI 0.40–0.88
P = 0.010
Cluster 3 vs Cluster 1
aOR 0.59 (95% CI 0.40–0.88); P = 0.010
Further findings
Model performance after adding phenotype to BMI category model
- Improved overall model fit; modest gains in discrimination and reclassification
Original publication
Association of body mass index and computed tomography-derived body composition with postoperative cardiovascular events: a secondary analysis of two prospective cohorts. Br J Anaesth. Published 1 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →