Pediatric anesthesia & critical care

Association Between Preoperative Sarcopenia and Early Postoperative Outcomes in Pediatric Patients Undergoing Total Correction of Tetralogy of Fallot: A Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

The incidence of sarcopenia, as assessed by preoperative chest CT, was low in pediatric patients undergoing total correction of TOF, and preoperative sarcopenia did not predict early postoperative major adverse events.

Study context

Population
Pediatric patients (≤3 years) undergoing total correction of tetralogy of Fallot (TOF), single university hospital, Seoul, South Korea, May 2008–February 2018included in final analysis
Participants
330 patients
Exposure
Preoperative sarcopenia vs presarcopenia vs no sarcopenia
  • Sarcopenian = 13
  • Presarcopenian = 57
  • No sarcopenian = 260reference
Outcome
Major adverse events
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

P = 0.033

Observational data: associations, not effects.

Further findings

Predictors of major adverse events (logistic regression): younger age at surgery

OR (95% CI)P value
Age at surgeryOnly significant factor0.82 (0.72–0.94)P = 0.003

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association Between Preoperative Sarcopenia and Early Postoperative Outcomes in Pediatric Patients Undergoing Total Correction of Tetralogy of Fallot: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 10 June 2023. doi:10.1053/j.jvca.2023.06.012

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