ICU sedation, delirium & recovery
Association of early mobility with the incidence of deep-vein thrombosis and mortality among critically ill patients: a post hoc analysis of PREVENT trial
Authors' conclusion
Early mobility was associated with reduced mortality, but not with different incidence of deep-vein thrombosis.
Study context
- Population
- Critically ill patients receiving pharmacologic thromboprophylaxis with an expected ICU stay ≥ 72 h
- Participants
- 1,708 patients
- Comparison
- Early mobility level 4-7 and 1-3 vs level 0 within the first 3 ICU days
- 4-7n = 85
- 1-3n = 356
- 0n = 1,267reference
- Primary endpoint
- Incident proximal lower-limb DVT
Methodological detailspost hoc analysis, multicentre
- Post hoc analysis
- Multicentre
Primary result
As reported in the abstract
Each group vs 0Adjusted hazard ratio (95% CI)P value
4-7
1.19(0.16–8.90)
P = 0.871-3
0.91(0.39–2.12)
P = 0.83Further findings
| Outcome | aHR (95% CI) | P value | |
|---|---|---|---|
| 90-day mortality · 90 days4-7 vs 0 | 0.47 (0.22–1.01) | P = 0.052 | |
| 90-day mortality · 90 days1-3 vs 0 | 0.43 (0.30–0.62) | P < 0.0001 | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Original publication
Association of early mobility with the incidence of deep-vein thrombosis and mortality among critically ill patients: a post hoc analysis of PREVENT trial. Crit Care. Published 3 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →