Cardiac arrest & resuscitation
Association of healthy sleep patterns with incident sudden cardiac arrest: a prospective study of 414,625 UK biobank participants
Main finding · Incident SCAResult — go to the resultHazard ratio 0.81 95 % CI 0.65–1.00Authors' conclusion
Healthy sleep patterns are associated with a significantly reduced risk of SCA, particularly among individuals younger than 60 years without cardiovascular disease, cerebrovascular disease, or cancer.
Study context
- Population
- UK Biobank participants2,545 incident sudden cardiac arrest (SCA) cases
- Participants
- 414,625 participants
- Exposure
- Healthy sleep score 4–5 vs 0–1
- Outcome
- Incident SCA
- Follow-up
- Median 13.93 years
Main finding
As reported in the abstract
Hazard ratio
0.81
95 % CI 0.65–1.00
Sleep score 4 or 5 vs Sleep score 0-1
HR 0.81 (95 % CI 0.65–1.00)
- Each one-point increase in sleep score: reduction in SCA risk
- 5 %
Observational data: associations, not effects.
Further findings
Dose-response (restricted cubic spline)
- Dose-response relationship, no evidence of nonlinearity
Potential SCA reduction if all had optimal sleep score of 5
- Incidence of SCA potentially reduced by
- 17.11 %
SCA by age and chronic conditions (subgroups)
- Association more pronounced in age <60 years and those without CHD, hypertension, stroke or cancer
Genetic correlation with SCA
- Sleep duration, insomnia and snoring showed significant genetic correlations with SCA
Original publication
Association of healthy sleep patterns with incident sudden cardiac arrest: a prospective study of 414,625 UK biobank participants. Resuscitation. Published 7 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →