Cardiac arrest & resuscitation

Association Between Capnographic Changes During Pulse Checks of Varying Durations and Clinical Outcomes During Cardiopulmonary Resuscitation: A Multicenter Study From Türkiye (CaPTuRe)

ResuscitationPublished multicenter, prospective, controlled, quasi-randomized study

Authors' conclusion

Pulse checks completed within 5 seconds were associated with more favorable capnographic dynamics and higher ROSC rates than those lasting 6-10 seconds. These findings are hypothesis-generating and warrant prospective validation.

Study context

Population
Cardiac arrest patients undergoing cardiopulmonary resuscitation (CPR), Türkiyecardiac arrest patients included · Group A 124 · Group B 128
Participants
252 patients
Comparison
Pulse checks ≤5 seconds vs >5 to ≤10 seconds
  • Group An = 124
  • Group Bn = 128reference

Primary result

As reported in the abstract

Capnographic parameters in patients with ROSC vs non-survivors, Group A
  • In Group A, patients with return of spontaneous circulation (ROSC) had markedly lower loss rates and shorter recovery times than non-survivors, together with higher pre- and post-CPR ETCO2 values (all p<0.001)

Further findings

OutcomeGroup AGroup BOR for ROSC (95% CI)P value
Return of spontaneous circulation (ROSC)36.3%19.5%2.39 (1.347–4.242)P = 0.003
  • Return of spontaneous circulation (ROSC): logistic regression; pulse check duration an independent predictor of ROSC
  • Return of spontaneous circulation (ROSC): ROSC rate p=0.005

Correlations between capnographic parameters

Pre-CPR ETCO2 vs loss rate
ρ=−0.770
Pre- vs Post-CPR ETCO2
ρ=0.96
Loss rate vs recovery time
ρ=0.89

Original publication

Association Between Capnographic Changes During Pulse Checks of Varying Durations and Clinical Outcomes During Cardiopulmonary Resuscitation: A Multicenter Study From Türkiye (CaPTuRe). Resuscitation. Published 20 October 2026. doi:10.1016/j.resuscitation.2026.111358

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