Paediatric anaesthesia & critical care

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest

ResuscitationPublished Retrospective cohort study

Main finding · Unfavorable outcome per increasing hypotension burden below 10th percentile-for-age (EHR-documented BPs)Result — go to the resultOdds ratio 4.64 95% CI [1.21, 17.6]

Authors' conclusion

Hypotension burden calculated using EHR-documented BPs was associated with unfavorable outcome after pediatric cardiac arrest and closely approximated hypotension burden from continuous high-resolution BPs.

Study context

Population
Children after cardiac arrest, 24 h following ROSCanalysed
Participants
139 children
Exposure
EHR-documented blood pressures (BPs) vs Continuous high-resolution BPs
Outcome
Unfavorable outcome (Pediatric Cerebral Performance Category Score ≥3 with change from pre-arrest), association with hypotension burden below 10th percentile for age
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Unfavorable outcome per increasing hypotension burden below 10th percentile-for-age (EHR-documented BPs)

Odds ratio

4.64

95% CI [1.21, 17.6]

P = 0.025

EHR-documented BPs
OR 4.64 (95% CI [1.21, 17.6]); P = 0.025

Per increasing hypotension burden below 10th percentile-for-age, as printed

Unfavorable outcome
63%

Observational data: associations, not effects.

Further findings

Hypotension burden, EHR-documented vs continuous high-resolution BPs · similar

P = 0.165

Bias between measurement modalities (Bland-Altman analysis)

No significant bias toward either measurement modality; mean difference
0.22 ± 0.95
  • p = 0.096

Original publication

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest. Resuscitation. Published 11 September 2026. doi:10.1016/j.resuscitation.2026.111308

Composed by AI from the published abstract and checked against it. How Briefs are made →

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