Perioperative medicine & outcomes
Association of non-anaemic iron deficiency with postoperative outcomes after fast-track hip and knee arthroplasty: a prospective cohort study
Authors' conclusion
The influence of iron deficiency on days alive and at home at 30 and 90 days after fast-track hip or knee arthroplasty was statistically significant, but of minimal clinical importance.
Study context
- Population
- Patients undergoing primary unilateral fast-track hip or knee arthroplasty, eight Danish departments
- Participants
- 964 vs 3,919
- Exposure
- Non-anaemic iron deficiency vs iron replete
- Iron deficientn = 964
- Iron repleten = 3,919reference
- Outcome
- Median DAH at POD 30 (DAH30) and POD 90 (DAH90), adjusted for procedure, hospital and comorbidity (quantile regression)
- Follow-up
- 30 and 90 days
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
DAH30 · 30 days
Each group vs iron repleteEstimate (95% CI)P value
Iron deficient
adjusted difference in median DAH30 −0.00 days(−0.00 to −0.00)
P = 0.001Iron deficient
adjusted difference in median DAH90 −0.00 days(−0.00 to −0.00)
P = 0.006- DAH30 differently distributed between groups
- P < 0.001
Observational data: associations, not effects.
Further findings
LOS >2 days, 30-day readmission, EQ-VAS at 90 days
- No association between iron deficiency and any of the other endpoints
Original publication
Association of non-anaemic iron deficiency with postoperative outcomes after fast-track hip and knee arthroplasty: a prospective cohort study. Br J Anaesth. Published 21 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →