Perioperative medicine & outcomes
Associations between non‐anaemic iron deficiency and outcomes following elective surgery for colorectal cancer: a prospective cohort study*
Authors' conclusion
In adult patients without anaemia undergoing surgery for colorectal cancer, iron deficiency defined by transferrin saturation < 20% was not associated with worse patient outcomes and appeared to be associated with more days alive and at home on postoperative day 90.
Study context
- Population
- Adults (≥ 18 y) without anaemia undergoing surgery for colorectal cancer, 16 hospitals in Australia and Aotearoa/New Zealand
- Participants
- 420 adults
- Exposure
- Iron deficiency vs iron-replete state
- Iron-deficientn = 170
- Iron-repleten = 250reference
- Outcome
- Days alive and at home
- Follow-up
- POD 90
Methodological detailsobservational, multicentre
- Observational
- Multicentre
Main finding
As reported in the abstract
Iron-deficient vs Iron-repleteDifference in medians, days (95% CI)P value
Unadjusted
0.9(0–1.8)
P = 0.047Adjusted; favouring the iron-deficient group
0.9(0–1.80)
P = 0.042Observational data: associations, not effects.
Original publication
Associations between non‐anaemic iron deficiency and outcomes following elective surgery for colorectal cancer: a prospective cohort study*. Anaesthesia. Published 15 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →