Haemodynamics, fluids & transfusion
Association of preoperative hemoglobin levels with intraoperative hypotension: a retrospective cohort study
Authors' conclusion
Lower preoperative hemoglobin levels were significantly associated with an increased risk of IOH and longer postoperative length of hospital stay. These findings highlight the potential value of incorporating hemoglobin level assessments into IOH risk stratification and may help improve patient outcomes.
Study context
- Population
- Patients aged ≥ 18 yr who underwent general anesthesia between 2019 and 2023
- Participants
- 2,060 patients
- Exposure
- Preoperative hemoglobin levels and intraoperative hypotension
- Outcome
- IOH at MBP < 65 and < 45 mm Hg
Main finding
As reported in the abstract
- No significant association between preoperative hemoglobin levels and intraoperative hypotension (IOH) risk at mean blood pressure (MBP) < 65 mm Hg
- P = 0.13
- No significant association between preoperative hemoglobin levels and IOH risk at MBP < 45 mm Hg
- P = 0.12
Observational data: associations, not effects.
Further findings
IOH at MBP < 60 mm Hg
- Lower preoperative hemoglobin levels associated with significantly higher risk of IOH
- P = 0.03
IOH at MBP < 55 mm Hg and < 50 mm Hg
- Similar trends at < 55 mm Hg
- 0.02
- Similar trends at < 50 mm Hg
- 0.03
IOH episodes and odds ratios
- Lower hemoglobin levels associated with more frequent IOH episodes and higher odds ratios
Postoperative length of hospital stay
- Significant association between lower preoperative hemoglobin levels and a longer postoperative length of hospital stay
- Generalized additive model
Original publication
Association of preoperative hemoglobin levels with intraoperative hypotension: a retrospective cohort study. Can J Anaesth. Published 12 October 2026. doi:10. 1007/ s12630-026-03207-2
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