Perioperative medicine & outcomes

Association of reintubation and hospital costs and its modification by postoperative surveillance: A multicenter retrospective cohort study

J Clin AnesthPublished Retrospective cohort study

Main finding · Direct hospital costsResult — go to the resultAdjusted model estimate 2.05 95% CI 2.00–2.10

Authors' conclusion

Postoperative reintubation is associated with 2-fold higher hospital costs. Prolonged surveillance in the recovery room mitigated this effect.

Study context

Population
Adult non-cardiac surgical patients under GA, 2016–2021, two tertiary academic networks in the Bronx, New York and Boston, Massachusetts, US
Participants
68,125 participants
Exposure
Unplanned reintubation within 7 days of surgery vs no reintubation
  • Reintubationn = 1,759
Outcome
Direct hospital costs associated with patient care related activities
Methodological detailsmulticentre, multivariable generalized linear model, Healthcare Cost and Utilization Project-National Inpatient Sample (HCUP-NIS) matched cohort
  • Multicentre
  • Multivariable generalized linear model
  • HCUP-NIS matched cohort

Main finding

Direct hospital costs

Adjusted model estimate

2.05

95% CI 2.00–2.10

As reported in the abstract

Adjusted absolute difference in costs, reintubation vs no reintubation (HCUP-NIS matched cohort)
US$ 18,837 (95% CI: 17,921-19,777)

Observational data: associations, not effects.

Further findings

OutcomeShorter PACU LOSLonger PACU LOSAdjusted absolute difference (US$) (95% CI)P value
Modification of reintubation–cost association by PACU surveillance (≥4 h)Reintubation, shorter PACU LOS vs No reintubation23,444 (21,217–25,799)
Modification of reintubation–cost association by PACU surveillance (≥4 h)Reintubation, longer PACU LOS vs No reintubation17,615 (16,350–18,926)
Timing of reintubation by PACU LOS (subgroup)median 2 (IQR 1–5) days1 (IQR 0–2) daysP < 0.001
  • Modification of reintubation–cost association by post-anesthesia care unit (PACU) surveillance (≥4 h): p-for-interaction <0.001
  • Modification of reintubation–cost association by PACU surveillance (≥4 h): shorter vs longer PACU stay p < .001

Original publication

Association of reintubation and hospital costs and its modification by postoperative surveillance: A multicenter retrospective cohort study. J Clin Anesth. Published 16 September 2023. doi:10.1016/j.jclinane.2023.111264

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