Perioperative medicine & outcomes

Association of sleep quality on the night of operative day with postoperative delirium in elderly patients: A prospective cohort study

Eur J AnaesthesiolPublished Prospective cohort study

Main finding · PODResult — go to the resultAdjusted odds ratio 1.43 95% CI 1.11–1.82

Authors' conclusion

The poor subjective sleep quality on the night of operative day was independently associated with increased POD risk, especially in certain subpopulations.

Study context

Population
Patients aged 65 years or older undergoing elective surgery under GA, tertiary hospital in Chinaincluded in the analysis
Participants
3,072 patients
Exposure
Sleep disturbance vs No sleep disturbance
  • Sleep disturbancen = 791
Outcome
Delirium incidence
Methodological detailssingle-centre
  • Single-centre

Main finding

POD

Adjusted odds ratio

1.43

95% CI 1.11–1.82

P = 0.005

Sleep disturbance vs No sleep disturbance
aOR 1.43 (95% CI 1.11–1.82); P = 0.005

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

Postoperative delirium (POD) by subgroup (subgroup)

Association significant in age 65-75 years, male sex, ASA III and IV, haemoglobin more than 12 g l −1, intra-operative hypotension, surgical duration more than 120 min, education 9 years or less; no interaction between subgroups

AKI, stroke, pulmonary infection, cardiovascular complications, all-cause mortality · within 1 year postoperatively

No significant differences

Original publication

Association of sleep quality on the night of operative day with postoperative delirium in elderly patients: A prospective cohort study. Eur J Anaesthesiol. Published 16 January 2024. doi:10.1097/eja.0000000000001952

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