ICU sedation, delirium & recovery
Association of socioeconomic deprivation with outcomes in critically ill adult patients: an observational prospective multicenter cohort study
Authors' conclusion
In a universal health care system, the most deprived socioeconomic phenotypes were not associated with increased 180-day mortality.
Study context
- Population
- Adults (≥ 18 years) admitted to eight ICUs in the Greater Paris area, March–June 2018
- Participants
- 1,748 adults · 8 ICUs
- Exposure
- Socioeconomic phenotypes B–E vs phenotype A
- Phenotype An = 958reference
- Phenotype Bn = 273
- Phenotype Cn = 117
- Phenotype En = 93
- Outcome
- Mortality
- Follow-up
- 180 days
Methodological detailsmulticentre, hierarchical clustering, Cox proportional hazards models
- Multicentre
- Hierarchical clustering
- Cox proportional hazards models
Main finding
As reported in the abstract
180-day mortality
Each group vs phenotype AHazard ratio (95% CI)
Phenotype B
0.85(0.65–1.12)
Phenotype C
0.56(0.34–0.93)
Phenotype D
1.09(0.78–1.51)
Phenotype E
1.20(0.73–1.96)
Observational data: associations, not effects.
Further findings
Patient characteristics by phenotype
- Phenotypes D and E younger, fewer comorbidities, more alcohol and opiate use, more often admitted for self-harm
- Phenotype C more often admitted with chronic respiratory diseases and received more non-invasive positive pressure ventilation
Original publication
Association of socioeconomic deprivation with outcomes in critically ill adult patients: an observational prospective multicenter cohort study. Ann Intensive Care. Published 9 April 2024. doi:10.
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