Perioperative medicine & outcomes
The association of the perioperative fluid balance and cardiopulmonary complications in emergency gastrointestinal surgery: exploration of a randomized trial
Primary resultResult — go to the resultOdds ratio 3.4 95% CI 1.5–7.6Authors' conclusion
Following emergency surgery for gastrointestinal obstruction or perforation, a fluid balance < 2.0 L was associated with decreased risk of cardiopulmonary complications without increasing renal complications.
Study context
- Population
- Patients undergoing emergency surgery for gastrointestinal obstruction or perforation
- Participants
- 303 patients
- Comparison
- Perioperative fluid balance high > 2 L or low < 0 L vs moderate 0-2 L
- Low-FBn = 44
- Moderate-FBn = 108reference
- High-FBn = 151
- Primary endpoint
- Cardiopulmonary complications
Methodological detailspropensity adjusted logistic regression
- Propensity adjusted logistic regression
Primary result
As reported in the abstract
Odds ratio
3.4
95% CI 1.5–7.6
P = 0.002
High-FB vs Moderate-FB
OR 3.4 (95% CI 1.5–7.6); P = 0.002
Further findings
Median, L
| Outcome | Low-FB | Moderate-FB | High-FB |
|---|---|---|---|
| Perioperative FB | −0.9 (IQR −1.4–-0.6) | 0.9 (IQR 0.5–1.3) | 3.8 (IQR 2.7–5.3) |
Original publication
The association of the perioperative fluid balance and cardiopulmonary complications in emergency gastrointestinal surgery: exploration of a randomized trial. Perioper Med (Lond). Published 26 April 2024. doi:10. 1186/ s13741-024-00390-y
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