Perioperative medicine & outcomes

External Validation of the National Emergency Laparotomy Audit (NELA) Prognostic Model in Emergency Abdominal Surgery

Acta Anaesthesiol ScandPublished External validation study of a prognostic model

Authors' conclusion

The P-NELA prognostic model had good discrimination in this external validation. The reduced number of variables in this model compared to the previous NELA risk prediction model did not affect performance.

Study context

Population
Adults undergoing emergency laparotomy or laparoscopy for surgical gastrointestinal conditions (perforation, obstruction, ischaemia), Copenhagen University Hospital-Herlev, 1 Nov 2017–31 Jan 2020
Participants
679 adults
Comparison
2023 NELA prognostic model vs 2020 NELA risk prediction model
Outcome
30-day mortality (model performance: scaled Brier score, AUC, Integrated Calibration Index)
Follow-up
30 days
Methodological detailssingle-centre
  • Single-centre

Performance

As reported in the abstract

30-day mortality prediction
Test or modelScaled Brier scoreAUC (95% CI)Integrated Calibration Index
P-NELA18%0.87 (0.83-0.90)0.042

P-NELA

Scaled Brier score18%
AUC (95% CI)0.87 (0.83-0.90)
Integrated Calibration Index0.042
Observed 30-day mortality
13.3% (90 patients)

Original publication

External Validation of the NELA Prognostic Model in Emergency Abdominal Surgery. Acta Anaesthesiol Scand. Published 26 September 2025. doi:10.1111/aas.70128

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