Pediatric anesthesia & critical care
Associations Between Complete Blood Count‐Derived Inflammation Indices and Emergence Delirium in Children Undergoing Adenotonsillectomy
Authors' conclusion
SII and PIV values derived from routine complete blood count parameters were observed to be associated with the development of ED in pediatric patients undergoing adenotonsillectomy and may provide useful insights into the potential role of systemic inflammation in the pathophysiology of such delirium.
Study context
- Population
- Children aged 3–12 years undergoing adenoidectomy or adenotonsillectomy
- Participants
- 99 children
- Exposure
- SII vs PIV
- Outcome
- Emergence delirium (Pediatric Anesthesia Emergence Delirium (PAED) scale) and its association with preoperative SII and PIV
Methodological detailsROC curve analysis, multivariable logistic regression
- ROC curve analysis
- Multivariable logistic regression
Main finding
As reported in the abstract
ED discrimination by preoperative inflammatory indices
| Group | AUC | Cut-off | Sensitivity | Specificity |
|---|---|---|---|---|
| SII | 0.850 | 412 | 81.3% | 86.6% |
| PIV | 0.883 | 289 | 75.0% | 92.5% |
AUC
SII0.850
PIV0.883
Cut-off
SII412
PIV289
Sensitivity
SII81.3%
PIV75.0%
Specificity
SII86.6%
PIV92.5%
- Emergence delirium (ED) incidence
- 32 out of 99 patients (32.3%)
Observational data: associations, not effects.
Original publication
Associations Between Complete Blood Count‐Derived Inflammation Indices and Emergence Delirium in Children Undergoing Adenotonsillectomy. Paediatr Anaesth. Published 14 May 2026. doi:10.
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