Perioperative medicine & outcomes
Associations between the intraoperative fraction of inspired intraoperative oxygen administration and days alive and out of hospital after surgery
Authors' conclusion
We found potential benefits, and risks, associated with liberal intraoperative oxygen administration
Study context
- Population
- Adults undergoing elective surgery lasting more than 2 h at a large metropolitan New Zealand hospital, 2012 to 2020
- Participants
- 15,449 adults
- Exposure
- Low and medium vs high mean intraoperative fraction of inspired oxygen (FiO2)
- Outcome
- DAOH at 90 days (DAOH90)
- Follow-up
- 90 days
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Each group vs highAdjusted mean difference, days (95% CI)P value
Medium
0.09(−0.06 to 0.25)
P = 0.25Low
0.28(−0.05 to 0.62)
P = 0.2Observational data: associations, not effects.
Secondary outcomes
| Outcome | aOR (95% CI) | |
|---|---|---|
| Surgical site infectionLow vs High | 1.53 (1.12–2.10) | |
| ICU admission | 1.1 (1.03–1.18) | |
| 0.512Adjusted odds ratio (log scale) |
Safety
| Outcome | aOR (95% CI) | |
|---|---|---|
| Respiratory complications | 1.17 (1.08–1.26) | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Associations between the intraoperative fraction of inspired intraoperative oxygen administration and days alive and out of hospital after surgery. BJA Open. Published 22 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →