Associations Between Social Determinants of Health and Opioid-Use Disorder Among Chronic Pain Patients From a Multi-Institutional Dataset
Authors' conclusion
The study revealed a significantly greater social disadvantage metric in chronic pain individuals with OUD.
Study context
- Population
- Patients with chronic pain in the All of Us dataset7,272 (10.1%) with opioid-use disorder (OUD)
- Participants
- 71,727 patients
- Exposure
- Social determinants of health domains and odds of OUD
- Outcome
- OUD-related diagnoses (eg, opioid dependence)
Methodological detailsmulti-institutional dataset (All of Us), mixed-effects multivariable regression (random effect zip code)
- Multi-institutional dataset (All of Us)
- Mixed-effects multivariable regression (random effect zip code)
Main finding
As reported in the abstract
Odds of OUD by social determinants of health (SDoH) domain
Odds ratio (95% CI)P value
Area Deprivation Indexpopulation-level survey data, n = 71,684
5.70(2.34–13.83)
P < 0.001Unemployed
1.91(1.59–2.31)
P < 0.001College degree or greater
0.48(0.39–0.59)
P < 0.001Delayed medical care
1.42(1.20–1.69)
P < 0.001Inability to afford medical care
1.37(1.16–1.63)
P < 0.001Never married or without a partner
1.49(1.28–1.73)
P < 0.001Observational data: associations, not effects.
Original publication
Associations Between Social Determinants of Health and Opioid-Use Disorder Among Chronic Pain Patients From a Multi-Institutional Dataset. Anesth Analg. Published 23 December 2024. doi:10.
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