Perioperative medicine & outcomes
Associations of an eye-tracking task and pupillary metrics with age and ASA physical status score in a preoperative cohort
Authors' conclusion
A preoperative 5 min VPC task and pupillometry are feasible tests in the preoperative setting and may provide a valuable window into an individual's cognition prior to elective surgery.
Study context
- Population
- Patients seen in the preoperative clinic at a tertiary academic center before elective surgeryanalysed
- Participants
- 199 participants
- Outcome
- Associations of VPC task score and pupillary metrics with age and ASA physical status; feasibility in the preoperative clinic
Methodological detailssingle-centre, tertiary academic center, 5 min visual paired comparison (VPC) task (Neurotrack) and pupillary light reflexes (PLR-3000) at the scheduled preoperative clinic visit
- Single-centre
- Tertiary academic center
- 5 min VPC task (Neurotrack) and pupillary light reflexes (PLR-3000) at the scheduled preoperative clinic visit
Main finding
As reported in the abstract
Associations with age, ASA and VPC score
- Age vs ASA physical status (Mann-Whitney U)
- p < 0.0001
- Age vs maximum pupil size (Spearman r = - 0.40)
- p < 0.0001
- Age vs maximum constriction velocity (Spearman r = - 0.39)
- p < 0.0001
- VPC score vs age (Spearman r = - 0.21)
- p = 0.0016
- VPC score vs ASA score (Kruskal-Wallis), no association
- p = 0.14
Observational data: associations, not effects.
Further findings
VPC score vs nonsurgical cohort with no history of memory impairment
- Preoperative population scored worse on VPC task (Mann-Whitney U)
- P = 0.0002
Cohort characteristics
- ASA 2
- 34%
- ASA 3
- 58%
- Median age (IQR: 44-69)
- 57
Original publication
Associations of an eye-tracking task and pupillary metrics with age and ASA physical status score in a preoperative cohort. J Clin Monit Comput. Published 28 January 2023. doi:10.
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