Perioperative medicine & outcomes

Associations of preoperative anaemia with healthcare resource use and outcomes after colorectal surgery: a population-based cohort study

Br J AnaesthPublished Population-based cohort study

Main findingResult — go to the resultRatio of means 1.05 95% CI 1.04–1.06

Authors' conclusion

Approximately $2671 CAD per person in 30-day health system costs are attributable to preoperative anaemia after colorectal surgery in Ontario, Canada.

Study context

Population
Ontario, Canada residents aged ≥18 yr undergoing elective colorectal resection, 2012–2022
Participants
54,286 participants
Exposure
Preoperative anaemia vs no preoperative anaemia
  • Anaemian = 21,264
Outcome
Costs in 2022 Canadian dollars (CAD), publicly funded healthcare system perspective
Follow-up
30 days
Methodological detailslinked, routinely collected data
  • Linked, routinely collected data

Main finding

As reported in the abstract

Ratio of means

1.05

95% CI 1.04–1.06

Anaemia vs Control
ratio of means 1.05 (95% CI 1.04–1.06)
Absolute adjusted cost increase per person attributable to preoperative anaemia
$2671

Observational data: associations, not effects.

Secondary outcomes

OutcomeEstimate
RBC transfusion · 30 daysOR 4.34 (95% CI 4.04–4.66)
LOS · 30 daysratio of means 1.08 (95% CI 1.07–1.10)
Readmissions · 30 daysOR 1.16 (95% CI 1.08–1.24)
DAH · 30 daysratio of means 0.95 (95% CI 0.95–0.96)

Safety

OutcomeOR (95% CI)
Major adverse events · 30 days1.14 (1.03–1.27)

Original publication

Associations of preoperative anaemia with healthcare resource use and outcomes after colorectal surgery: a population-based cohort study. Br J Anaesth. Published 20 April 2024. doi:10.1016/j.bja.2024.03.018

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