Perioperative medicine & outcomes

Temporal trends in postoperative outcomes after major abdominal surgery: a population-based cohort study

Br J AnaesthPublished Population-based cohort study

Authors' conclusion

Despite advances in perioperative protocols and techniques, the overall adjusted rate of moderate-to-severe complications did not change over time. Contrasting trends were evident between different surgical procedures.

Study context

Population
Adults undergoing major elective abdominal surgery (gastroesophagectomy, pancreaticoduodenectomy, partial hepatectomy, colorectal resection), Ontario, Canada, 2005–21
Participants
148,725 adults
Exposure
Temporal trends over 2005-21
Outcome
Composite of moderate-to-severe postoperative complications
Methodological detailscase-mix adjusted linear trends
  • Case-mix adjusted linear trends

Main finding

As reported in the abstract

Yearly rate of moderate-to-severe complications

Yearly rate of moderate-to-severe complications similar over time, RR

0.994

95% CI 0.985–1.002

Observational data: associations, not effects.

Secondary outcomes

Health system outcomes (yearly trend)

LOS, RR
0.968 (95% CI 0.959-0.977)
ICU admission, RR
0.982 (95% CI 0.966-0.998)
Days alive and at home, RR
1.004 (95% CI 1.003-1.005)
Total costs, RR
0.990 (95% CI 0.982-0.997)
  • Temporal improvements

Complication rates by procedure (subgroup, yearly trend)

Colorectal resection, RR (95% CI 0.980-0.997), improved
0.988
Gastroesophagectomy, RR (95% CI 0.974-0.996), improved
0.985
Partial hepatectomy, RR (95% CI 1.003-1.022), increased
1.012
Pancreaticoduodenectomy, RR (95% CI 1.004-1.028), increased
1.016

Original publication

Temporal trends in postoperative outcomes after major abdominal surgery: a population-based cohort study. Br J Anaesth. Published 23 October 2025. doi:10.1016/j.bja.2025.08.030

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