Cardiac arrest & resuscitation
Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest
Authors' conclusion
ROSC patients with STEMI on out-of-hospital ECG commonly resolve in the ED (67%).
Study context
- Population
- Adults (≥18 years) with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA), ≥1 out-of-hospital and emergency department (ED) ECG, transported to the study hospital49 with out-of-hospital STEMI
- Participants
- 176 adults
- Comparison
- Resolved vs persistent STEMI on ED ECG after out-of-hospital STEMI ECG
- Resolved STEMIn = 33
- STEMI on ED ECGn = 16reference
- Primary endpoint
- Resolution of out-of-hospital STEMI criteria on ED ECG
Primary result
As reported in the abstract
Resolution of out-of-hospital STEMI on ED ECG
STEMI resolved upon ED evaluation (33/49)
67%
Further findings
| Outcome | Resolved STEMI | P value |
|---|---|---|
| Resuscitation timeResolved STEMI vs Persistent STEMI | 13 (IQR 5–18) minutes | P = 0.007 |
| Epinephrine doseResolved STEMI vs Persistent STEMI | 3 (IQR 1–4) milligrams | P = 0.018 |
| Norepinephrine useResolved STEMI vs Persistent STEMI | 15% | P ≤ 0.001 |
| Time from ROSC to out-of-hospital ECGResolved STEMI vs Persistent STEMI | 5.5 (IQR 1–8) minutes | P = 0.044 |
| Time between out-of-hospital and ED ECGResolved STEMI vs Persistent STEMI | 34 (IQR 25–52) minutes | P = 0.001 |
- Resuscitation time: Persistent STEMI 21 (IQR 14–28) minutes
- Epinephrine dose: Persistent STEMI 5 (IQR 2–10) milligrams
- Norepinephrine use: Persistent STEMI 69%
- Time from ROSC to out-of-hospital ECG: Persistent STEMI 8.5 (IQR 7–14) minutes
- Time between out-of-hospital and ED ECG: Persistent STEMI 21 (IQR 14–27) minutes
Ischemia on ED ECG, patients with non-STEMI out-of-hospital electrocardiograms (ECGs) (subgroup)
- More defibrillations associated with increased ischemia on ED ECG
Original publication
Associations with resolution of ST-segment elevation myocardial infarction criteria on out-of-hospital 12-lead electrocardiograms following resuscitation from cardiac arrest. Resuscitation. Published 6 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →