Cardiac arrest & resuscitation
Association of Electrocardiographic Patterns After Successfully Resuscitated Out-of-Hospital Cardiac Arrest With Significant Coronary Lesions and Mortality—A Predefined Substudy of the Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation (TOMAHAWK) Trial
Authors' conclusion
Standardized 12-lead electrocardiogram patterns after ROSC at hospital admission in patients with successfully resuscitated OHCA without ST-segment elevations have poor predictive performance for the presence of significant coronary lesions.
Study context
- Population
- Adults with successfully resuscitated out-of-hospital cardiac arrest (OHCA) without ST-segment elevation; first ECG after return of spontaneous circulation (ROSC) at hospital admissionwith coronary angiography
- Participants
- 412 adults
- Primary endpoint
- Significant coronary lesions and 30-day mortality
Methodological detailspredefined subanalysis, multicentre, international
- Predefined subanalysis
- Multicentre
- International
Primary result
As reported in the abstract
Significant coronary lesions
Patients with significant coronary lesions
163
40%
Further findings
30-day mortality (total cohort with and without coronary angiography)
- Right BBB, prolonged intrinsicoid deflection time and intrinsicoid deflections in right BBB strong, independent predictors of 30-day mortality; predictive performance better than for coronary lesions
Original publication
Association of Electrocardiographic Patterns After Successfully Resuscitated Out-of-Hospital Cardiac Arrest With Significant Coronary Lesions and Mortality—A Predefined Substudy of the Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation (TOMAHAWK) Trial. Crit Care Med. Published 24 February 2025. doi:10.
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