Cardiac arrest & resuscitation
Coronary angiography findings in resuscitated and refractory out-of-hospital cardiac arrest: A systematic review and meta-analysis
Authors' conclusion
Patients with OHCA have a high prevalence of significant CAD caused by acute and treatable coronary lesions. Refractory OHCA was associated with more severe coronary lesions. CAD was also present in patients with nonshockable rhythm and without ST elevation.
Study context
- Population
- Patients after out-of-hospital cardiac arrest (OHCA) undergoing coronary angiography
- Participants
- 62,845 patients · 128 studies
- Comparison
- Refractory OHCA vs ROSC
- Outcome
- Location and rate of coronary lesions
Methodological detailsmeta-analysis of proportion, PubMed, Embase and Cochrane CENTRAL searched up to October 31, 2022
- Meta-analysis of proportion
- PubMed, Embase and Cochrane CENTRAL searched up to October 31, 2022
Pooled result
As reported in the abstract
Coronary angiography findings (pooled)
- Coronary angiography (CAG) performed
- 69% (63-75%)
- Significant coronary artery disease (CAD)
- 75% (70-79%)
- Culprit lesion
- 63% (59-66%)
- Multivessel disease
- 46% (41-51%)
- Left anterior descending artery most frequently involved
- 34% [30-39%]
Further pooled results
| Outcome | Refractory OHCA | P value |
|---|---|---|
| Left main involvementRefractory OHCA vs ROSC | 17% (95% CI 12–24%) | P = 0.002 |
| Acute occlusion of left anterior descending arteryRefractory OHCA vs ROSC | 27% (95% CI 17–39%) | P = 0.02 |
- Left main involvement: ROSC 5.7% (95% CI 3.1–10%)
- Acute occlusion of left anterior descending artery: ROSC 15% (95% CI 13–18%)
Significant CAD in nonshockable patients without ST-elevation (subgroup)
- Received CAG less frequently, despite significant disease
- 54% (31-76%)
Original publication
Coronary angiography findings in resuscitated and refractory out-of-hospital cardiac arrest: A systematic review and meta-analysis. Resuscitation. Published 9 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →