Cardiac arrest & resuscitation
Augmented Reality–Guided Decision Support in Simulated Pediatric Cardiac Arrest: A Randomized Clinical Trial
Primary resultResult — go to the resultMean difference −16.6 seconds 95% CI −51.3 to 17.0Authors' conclusion
In this randomized clinical trial, AR support did not clearly improve time to first epinephrine in simulated pediatric cardiac arrest, with estimates compatible with both benefit and little or no effect. It improved adherence to epinephrine dosing intervals without impairing other performance domains.
Study context
- Population
- Teams of pediatric nurses and physicians managing a standardized 12-minute simulated pediatric in-hospital cardiac arrest (IHCA) due to hyperkalemia, 2 tertiary pediatric emergency centers (Geneva, Switzerland and Alberta, Canada)18 teams
- Participants
- 54 participants
- Comparison
- Intervention vs Control
- Interventionn = 9 teams (27 participants)
- Controln = 9 teams (27 participants)reference
- Primary endpoint
- Time from recognition of loss of pulse to first epinephrine
Methodological detailsopen-label, multicentre, simulation-based, Conducted April to May 2025
- Open-label
- Multicentre
- Simulation-based
- Conducted April to May 2025
Primary result
As reported in the abstract
Mean difference
−16.6 seconds
95% CI −51.3 to 17.0
P = 0.40
By group
Intervention vs Control
mean difference −16.6 seconds (95% CI −51.3 to 17.0); P = 0.40
Secondary outcomes
Mean, seconds
| Outcome | Intervention | Control | Mean difference (seconds) (95% CI) | P value | |
|---|---|---|---|---|---|
| Deviation from 4-minute target for subsequent epinephrine | 17.2 (SD 32.5) | 49.7 (SD 40.3) | −32.4 (−58.8 to −5.8) | P = 0.03 | |
| −100−50050Difference, seconds (linear scale) |
| Outcome | Intervention | Control | Risk difference (95% CI) | |
|---|---|---|---|---|
| Epinephrine dosing guideline violations | 11% | 43% | −0.32 (−0.55 to −0.05) | |
| −1−0.500.5Difference (linear scale) |
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Epinephrine dosing guideline violations | 0.25 (0.06–0.996) | P = 0.03 | |
| 0.050.21520Relative risk (log scale) |
- Epinephrine dosing guideline violations: 2 of 19 vs 9 of 21 participants
Time to first defibrillation and adherence to 2-minute cycles
- Similar between groups
Chest compression fraction, peri-shock pauses, medication-dosing accuracy
- No meaningful between-group difference suggested
User experience and technology acceptance
- Favorable
Original publication
Augmented Reality–Guided Decision Support in Simulated Pediatric Cardiac Arrest: A Randomized Clinical Trial. JAMA Netw Open. Published 1 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →