Cardiac arrest & resuscitation

Automatic Mechanical Ventilation vs Manual Bag Ventilation During CPR: A Pilot Randomized Controlled Trial

ChestPublished Randomised controlled trial

Authors' conclusion

In this pilot trial, the use of MV instead of BV during CPR was feasible and could serve as a viable alternative.

Study context

Population
Patients with medical out-of-hospital cardiac arrest (OHCA) arriving at the ED
Participants
60 patients
Comparison
Automatic mechanical ventilation vs manual bag ventilation during CPR
  • Mechanical ventilation (MV)n = 30
  • Bag ventilation (BV)n = 30reference
Primary endpoint
Any return of spontaneous circulation (ROSC)
Methodological detailspilot
  • Pilot

Primary result

As reported in the abstract

P = 0.439

Secondary outcomes

OutcomeP value
Tidal volume and minute volumeMV vs BV · tidal volume significantly lower in MVP < 0.001
Tidal volume and minute volumeMV vs BV · minute volume significantly lower in MVP = 0.009

Changes in arterial blood gas results (pH, Pco2, Po2, bicarbonate, lactate) during CPR

No significant differences between groups; P values pH .798, Pco2 0.249, Po2 .515, bicarbonate .876, lactate .878

Original publication

Automatic Mechanical Ventilation vs Manual Bag Ventilation During CPR: A Pilot Randomized Controlled Trial. Chest. Published 18 February 2024. doi:10.1016/j.chest.2024.02.020

Composed by AI from the published abstract and checked against it. How Briefs are made →

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