Safety, quality & education

Bacterial contamination and greenhouse gas emissions: A randomised study of reuse versus single-use of infusion-set components for intravenous anaesthesia

Eur J AnaesthesiolPublished Randomised controlled trial

Primary resultResult — go to the resultRelative risk 0.84 95% CI 0.12–5.93

Authors' conclusion

We conclude that the prevalence of bacterial contamination was low for both methods.

Study context

Population
Operating rooms scheduled for TIVA54 operating rooms per method
Participants
189 vs 159
Comparison
Infusion-set reuse vs single use
  • Reusen = 189
  • Single usen = 159reference
Primary endpoint
Infusion-set bacterial contamination (aerobic culture of infusion-set fluid collected after each procedure)
Methodological detailscluster (operating rooms randomised), prespecified interim analysis
  • Cluster (operating rooms randomised)
  • Prespecified interim analysis

Primary result

As reported in the abstract

Relative risk

0.84

95% CI 0.12–5.93

P = 0.861

Events by treatment group

Reuse

2

events

Single use

2

events

Reuse vs Single use
RR 0.84 (95% CI 0.12–5.93); P = 0.861
Prevalence of positive cultures, overall
1.15% (0.03 to 2.27)

Secondary outcomes

Median, kg CO 2 -eq

OutcomeReuseSingle useDifference (kg CO 2 -eq) (95% CI)P value
Per-procedure CO2 emissions (life cycle assessment)0.43 (95% CI 0.41–0.47)1.39 (95% CI 1.37–1.40)−0.96 (−0.99 to −0.93)P < 0.0005
OutcomeReuseSingle use
Procedures per reused infusion setmedian three (range 1–8) procedures— not stated in the abstract

— not stated in the abstract

Per-procedure CO2 emissions (life cycle assessment)

Main emission sources: production of infusion-set components and waste handling

Original publication

Bacterial contamination and greenhouse gas emissions: A randomised study of reuse versus single-use of infusion-set components for intravenous anaesthesia. Eur J Anaesthesiol. Published 18 September 2024. doi:10.1097/eja.0000000000002067

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