Bacterial contamination and greenhouse gas emissions: A randomised study of reuse versus single-use of infusion-set components for intravenous anaesthesia
Primary resultResult — go to the resultRelative risk 0.84 95% CI 0.12–5.93Authors' conclusion
We conclude that the prevalence of bacterial contamination was low for both methods.
Study context
- Population
- Operating rooms scheduled for TIVA54 operating rooms per method
- Participants
- 189 vs 159
- Comparison
- Infusion-set reuse vs single use
- Reusen = 189
- Single usen = 159reference
- Primary endpoint
- Infusion-set bacterial contamination (aerobic culture of infusion-set fluid collected after each procedure)
Methodological detailscluster (operating rooms randomised), prespecified interim analysis
- Cluster (operating rooms randomised)
- Prespecified interim analysis
Primary result
As reported in the abstract
Relative risk
0.84
95% CI 0.12–5.93
P = 0.861
Events by treatment group
Reuse
2
events
Single use
2
events
Reuse vs Single use
RR 0.84 (95% CI 0.12–5.93); P = 0.861
- Prevalence of positive cultures, overall
- 1.15% (0.03 to 2.27)
Secondary outcomes
Median, kg CO 2 -eq
| Outcome | Reuse | Single use | Difference (kg CO 2 -eq) (95% CI) | P value | |
|---|---|---|---|---|---|
| Per-procedure CO2 emissions (life cycle assessment) | 0.43 (95% CI 0.41–0.47) | 1.39 (95% CI 1.37–1.40) | −0.96 (−0.99 to −0.93) | P < 0.0005 | |
| −1−0.500.5Difference, kg CO 2 -eq (linear scale) |
| Outcome | Reuse | Single use |
|---|---|---|
| Procedures per reused infusion set | median three (range 1–8) procedures | — not stated in the abstract |
— not stated in the abstract
Per-procedure CO2 emissions (life cycle assessment)
- Main emission sources: production of infusion-set components and waste handling
Original publication
Bacterial contamination and greenhouse gas emissions: A randomised study of reuse versus single-use of infusion-set components for intravenous anaesthesia. Eur J Anaesthesiol. Published 18 September 2024. doi:10. 1097/ eja. 0000000000002067
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