Basic analgesic use in randomised trials assessing local and regional analgesic interventions for mastectomy: a critical appraisal and clinical implications
Authors' conclusion
Consequently, the conclusions of the RCTs assessing local/regional analgesic techniques for mastectomy should be interpreted with caution.
Study context
- Population
- Randomised clinical trials (RCTs) evaluating local/regional analgesic techniques in patients undergoing mastectomy (PubMed, January 1, 2010 to May 31, 2023)
- Participants
- 92 RCTs
- Outcome
- Use of basic analgesics (paracetamol, NSAIDs, cyclooxygenase-2 specific inhibitors, dexamethasone) in comparator groups
Main finding
As reported in the abstract
RCTs not administering basic analgesics in comparator groups
RCTs not administering well accepted basic analgesics in comparator groups
82 of 92
almost 90%
Original publication
Basic analgesic use in randomised trials assessing local and regional analgesic interventions for mastectomy: a critical appraisal and clinical implications. Br J Anaesth. Published 15 September 2023. doi:10.
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