Respiratory failure & ventilation
Beyond recovery: long-term cardiovascular risks after severe COVID-19 requiring intensive care
Main finding · ASCVDResult — go to the resultSubdistribution hazard ratio 1.42 95% CI 1.26–1.60Authors' conclusion
Among ICU-treated survivors of severe COVID-19, the risk of ASCVD, heart failure, atrial fibrillation, and all-cause mortality was increased during three years of follow-up compared with the matched population-based controls, with associations strongest during the first year of follow-up [period-specific estimates are provided in the Supplementary].
Study context
- Population
- Adults with confirmed COVID-19 requiring mechanical ventilation in the intensive care unit (ICU), discharged alive, Swedenpropensity-matched
- Participants
- 16,530 adults
- Exposure
- Cases vs Controls
- Casesn = 3,350
- Controlsn = 13,180reference
- Outcome
- Atherosclerotic cardiovascular disease (ASCVD) events occurring more than 30 days after ICU discharge
- Follow-up
- three-year follow-up
Methodological details1:4 propensity score matched, Swedish Intensive Care Registry
- 1:4 propensity score matched
- Swedish Intensive Care Registry
Main finding
ASCVD
Subdistribution hazard ratio
1.42
95% CI 1.26–1.60
Cases vs Controls
sHR 1.42 (95% CI 1.26–1.60)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Estimate | |
|---|---|---|
| Hospitalization with AF | sHR 1.85 (95% CI 1.64–2.10) | |
| Hospitalization for HF | sHR 1.81 (95% CI 1.57–2.09) | |
| All-cause mortality | HR 1.48 (95% CI 1.26–1.74) | |
| 0.512Ratio (log scale) |
Original publication
Beyond recovery: long-term cardiovascular risks after severe COVID-19 requiring intensive care. Crit Care. Published 25 May 2026. doi:10. 1186/ s13054-026-06088-5
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