Black representation in critical care randomized controlled trials: a meta-epidemiological study
Authors' conclusion
Black people are under-represented in critical care RCTs compared with site-level city-based demographics.
Study context
- Population
- Critically ill adults enrolled at USA or Canadian sites in critical care randomized controlled trials (RCTs) published in general medicine and intensive care unit (ICU) journals, 2016–202021 RCTs
- Comparison
- Black representation in critical care RCTs vs site-level city-based demographics
- Outcome
- Black representation vs population-based city demographics
Methodological detailsrandom effects model, meta-regression, 17 RCTs USA-only sites, 2 Canadian-only, 2 both
- Random effects model
- Meta-regression
- 17 RCTs USA-only sites, 2 Canadian-only, 2 both
Main finding
As reported in the abstract
Black people under-represented in critical care RCTs
6%
95% CI 1 to 11
Further findings
Sources of heterogeneity (meta-regression)
- Country of study site the only significant source of heterogeneity
- P = 0.02
- After controlling for pertinent variables
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Black representation in critical care randomized controlled trials: a meta-epidemiological study. Can J Anaesth. Published 12 May 2023. doi:10. 1007/ s12630-023-02462-x
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