Safety, quality & education

Black representation in critical care randomized controlled trials: a meta-epidemiological study

Can J AnaesthPublished Meta-epidemiological study

Authors' conclusion

Black people are under-represented in critical care RCTs compared with site-level city-based demographics.

Study context

Population
Critically ill adults enrolled at USA or Canadian sites in critical care randomized controlled trials (RCTs) published in general medicine and intensive care unit (ICU) journals, 2016–202021 RCTs
Comparison
Black representation in critical care RCTs vs site-level city-based demographics
Outcome
Black representation vs population-based city demographics
Methodological detailsrandom effects model, meta-regression, 17 RCTs USA-only sites, 2 Canadian-only, 2 both
  • Random effects model
  • Meta-regression
  • 17 RCTs USA-only sites, 2 Canadian-only, 2 both

Main finding

As reported in the abstract

Black people under-represented in critical care RCTs

6%

95% CI 1 to 11

Further findings

Sources of heterogeneity (meta-regression)

Country of study site the only significant source of heterogeneity
P = 0.02
  • After controlling for pertinent variables

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Black representation in critical care randomized controlled trials: a meta-epidemiological study. Can J Anaesth. Published 12 May 2023. doi:10.1007/s12630-023-02462-x

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