Obstetric anaesthesia

Burden of sepsis in obstetric critically ill patients: A qualitative systematic review

Anaesth Crit Care Pain MedPublished qualitative systematic review

Authors' conclusion

Robust epidemiological monitoring is therefore urgently required.

Study context

Population
Women requiring intensive care unit (ICU) admission for sepsis during pregnancy or the post-partumstudies met the inclusion criteria, of the 5847 screened studies · hospitalised obstetric patients 7,434,710 · obstetric ICU admissions for sepsis 3,593
Participants
25 women
Outcome
Incidence of intensive care unit admissions
Methodological detailsall included studies observational, studies published between 2013 and 2025
  • All included studies observational
  • Studies published between 2013 and 2025

Pooled result

As reported in the abstract

Range, every 10,000 hospitalized obstetric patients

21 to 857

Among hospitalized obstetric patients with sepsis, reached

11.3%

Further pooled results

Share of obstetric ICU admissions accounted for by sepsis

Sepsis accounted for, of obstetric ICU admissions
5.7%

Organ dysfunction

Half of the patients had one organ dysfunction, a quarter had three or more; respiratory and cardiovascular insufficiencies most common

Infection sources

Main sources were the genital, respiratory, and urinary tracts

Septic shock

Septic shock, of the cases
16.6%

Severity scores

Mean Sequential Organ Failure Assessment (SOFA) score
6.2
APACHE II score
12.3

ICU and hospital stay

Days

ICU stay
3
Hospital stay
8

Mortality

Median mortality
4.6%
Mortality varied significantly, with marked disparities between high- and low-income countries

Original publication

Burden of sepsis in obstetric critically ill patients: A qualitative systematic review. Anaesth Crit Care Pain Med. Published 6 October 2026. doi:10.1016/j.accpm.2026.101927

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