Pediatric anesthesia & critical care
Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes
Authors' conclusion
Calcium use was common during paediatric in-hospital cardiac arrest and associated with worse outcomes at hospital discharge.
Study context
- Population
- Children 37 weeks post-conceptual age to 18 years receiving chest compressions in 18 ICUs, October 2016-March 2021
- Participants
- 1,100 in-hospital cardiac arrests
- Comparison
- Calcium vs no calcium during paediatric in-hospital cardiac arrest
- Calciumn = 450
- Primary endpoint
- Sustained return of spontaneous circulation (ROSC), survival to hospital discharge, and survival to hospital discharge with favourable neurologic outcome
- Follow-up
- Hospital discharge
Methodological detailsprospective observational data, propensity-score weighted, 18 ICUs
- Prospective observational data
- Propensity-score weighted
- 18 ICUs
Primary result
As reported in the abstract
Calcium vs No calciumAdjusted odds ratio (95% CI)P value
Sustained ROSC
0.87(0.61–1.24)
P = 0.445Survival to hospital discharge
0.68(0.52–0.89)
P = 0.005Survival with favourable neurologic outcome at discharge
0.75(0.57–0.98)
P = 0.038Further findings
Survival to hospital discharge, by subgroup
- Calcium use associated with lower survival to hospital discharge in children with sepsis and renal insufficiency
Original publication
Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes. Resuscitation. Published 21 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →