Perioperative medicine & outcomes
Cannabis Use Disorder and Perioperative Complications
Main findingResult — go to the resultAdjusted odds ratio 1.19 95% CI 1.04–1.37Authors' conclusion
In this cohort study, cannabis use disorder was associated with a modest increased risk of perioperative morbidity and mortality after major elective, inpatient, noncardiac surgery.
Study context
- Population
- Adults aged 18 to 65 years undergoing major elective inpatient noncardiac surgery, US National Inpatient Sample, 2016–2019hospitalizations, matched cohort
- Participants
- 12,422 adults
- Exposure
- Cannabis use disorder vs no cannabis use disorder
- Cannabis use disordern = 6,211
- No cannabis use disordern = 6,211reference
- Outcome
- Composite of:
- In-hospital mortality
- 7 major perioperative complications (myocardial ischemia, AKI, stroke, respiratory failure, VTE, hospital-acquired infection, surgical procedure-related complications)
Methodological detailspopulation-based, propensity-score matched, 1:1 matched cohort
- Population-based
- Propensity-score matched
- 1:1 matched cohort
Main finding
As reported in the abstract
Adjusted odds ratio
1.19
95% CI 1.04–1.37
P = 0.01
Events by group
Cannabis use disorder vs No cannabis use disorder
aOR 1.19 (95% CI 1.04–1.37); P = 0.01
Observational data: associations, not effects.
Original publication
Cannabis Use Disorder and Perioperative Complications. JAMA Surg. Published 1 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →