Perioperative medicine & outcomes
Postoperative Delirium After Coronary Artery Bypass Grafting in the United States, 2016-2021: Trends, Risk Factors, and Outcomes
Main finding · Incidence of PODResult — go to the resultOdds ratio 1.04Authors' conclusion
POD after CABG is a common and costly complication.
Study context
- Population
- Adults ≥18 years undergoing isolated coronary artery bypass grafting (CABG), US National Inpatient Sample, 2016–2021
- Participants
- 911,910 CABG hospitalizations
- Exposure
- Postoperative delirium (POD) vs no POD after isolated CABG
- Outcome
- Incidence of POD
Methodological detailsdischarge weights and survey-specific analytic methods, National Inpatient Sample
- Discharge weights and survey-specific analytic methods
- National Inpatient Sample
Main finding
As reported in the abstract
Odds ratio
1.04
P < 0.001
- POD incidence
- 4.91%
Observational data: associations, not effects.
Further findings
Factors associated with POD (multivariable)
| aOR | P value | |
|---|---|---|
| Pre-existing dementiaStrongest associations after multivariable adjustment | 4.28 | P < 0.001 |
| Alcohol abuseStrongest associations after multivariable adjustment | 3.38 | P < 0.001 |
| Psychotic disordersStrongest associations after multivariable adjustment | 2.40 | P < 0.001 |
| Outcome | Estimate | P value |
|---|---|---|
| Mortality | aOR 1.85 | P < 0.001 |
| LOS | difference four days longer | P < 0.001 |
| Hospitalization costs | difference $8,565 higher costs | P < 0.001 |
Major complications
- POD independently associated with major complications
Original publication
Postoperative Delirium After Coronary Artery Bypass Grafting in the United States, 2016-2021: Trends, Risk Factors, and Outcomes. J Cardiothorac Vasc Anesth. Published 12 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →