Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study
Authors' conclusion
Cannabinoid-use disorders were present in 0.8% of ICU admissions in our region and were associated with increased ICU length of stay.
Study context
- Population
- Adults admitted to four public Australian ICUs
- Participants
- 28,689 adults · 34,680 admissions
- Exposure
- Cannabinoid-use disorders vs none
- Cannabinoid-use disordersn = 292
- Outcome
- Prevalence of cannabinoid-use disorders among ICU admissions and impact on survival
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Prevalence of cannabinoid-related diagnosis among ICU admissions
- Admissions with an associated diagnosis related to cannabinoids
- 292 (0.8%)
- Classified as harmful use
- 66%
- Dependence syndrome/withdrawal state
- 26%
- Psychosis/delirium
- 4%
- Acute intoxication
- 4%
Observational data: associations, not effects.
Further findings
90-day case-fatality · unadjusted
P = 0.034
ICU LOS
P < 0.0001
- 90-day case-fatality — No significant effect on mortality after adjustment for severity of illness, age, and chronic comorbidities
- p = 1.0
Patient characteristics
- Cannabinoid-use disorders more likely male
- 73%
- Younger (36 vs 62 years), fewer comorbidities, lesser severity of disease
Original publication
Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study. J Crit Care. Published 20 December 2023. doi:10.
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