Cardiac arrest & resuscitation
Centralization of post-resuscitation care after out-of-hospital cardiac arrest at cardiac arrest centres: a Danish nationwide follow-up study
Main finding · 30-day mortality, effect of centralizationResult — go to the resultAbsolute risk reduction 7% 95% CI 2%–11%Authors' conclusion
Centralization was associated with a significant reduction of the absolute 30-day mortality risk of 7% after accounting for regional differences, time-trends in patients, and OHCA characteristics.
Study context
- Population
- Consecutive adult out-of-hospital cardiac arrest (OHCA) patients with presumed cardiac cause admitted to a hospital, Denmark, 2007–2020
- Participants
- 14,276 patients
- Exposure
- CACs vs non-CACs
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailsdifference-in-difference model with repeated cross-sections, adjusted for known covariates
- Difference-in-difference model with repeated cross-sections
- Adjusted for known covariates
Main finding
30-day mortality, effect of centralization
Absolute risk reduction
7%
95% CI 2%–11%
As reported in the abstract
Observational data: associations, not effects.
Further findings
Temporal trend in 30-day mortality, 2007 to 2020
- CACs: 30-day mortality reduced from 66 to 47%
- non-CACs: 30-day mortality reduced from 92 to 74%
Original publication
Centralization of post-resuscitation care after out-of-hospital cardiac arrest at cardiac arrest centres: a Danish nationwide follow-up study. Crit Care. Published 14 February 2026. doi:10.
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