Pediatric anesthesia & critical care
Changes in the Term Neonatal Electroencephalogram with General Anesthesia: A Systematic Review with Narrative Synthesis
Authors' conclusion
Although evidence gaps were identified, both increasing sevoflurane concentration and decreasing temperature are associated with increasing discontinuity.
Study context
- Population
- Term neonates (37 to 44 weeks postmenstrual age) undergoing GA for cardiac or noncardiac surgery9 publications
- Participants
- 140 neonates
- Outcome
- EEG changes during GA
Methodological detailsROBINS-I risk of bias, GRADE quality of evidence, Search of MEDLINE, Embase, PubMed and Cochrane Library to November 2023; English language
- ROBINS-I risk of bias
- GRADE quality of evidence
- Search of MEDLINE, Embase, PubMed and Cochrane Library to November 2023; English language
Pooled result
As reported in the abstract
Discontinuity with GA (neonates)
94 of 119
Discontinuity with hypothermia (neonates)
23 of 23
Decreased delta (0.5 to 4 Hz) power with increasing anesthetic dose (neonates)
22
Original publication
Changes in the Term Neonatal Electroencephalogram with General Anesthesia: A Systematic Review with Narrative Synthesis. Anesthesiology. Published 22 May 2024. doi:10.
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