Paediatric anaesthesia & critical care
Characteristics and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (E-CPR): a nationwide retrospective analysis from the French pediatric ECMO Network
Authors' conclusion
E-CPR is mostly performed in children with heart disease, with limited use in out-of-hospital settings.
Study context
- Population
- Children (0–18 years) undergoing ECPR for intra- or extra-hospital refractory cardiac arrest, French pediatric ECMO network, 2019–2023
- Participants
- 164 children
- Outcome
- Incidence and outcomes of ECPR (survival)
Methodological detailsnationwide, multicentre network
- Nationwide
- Multicentre network
Main finding
As reported in the abstract
Survival
Survival at PICU discharge
29.9%
Survival at hospital discharge
29.3%
Survival after one year
27.4%
Observational data: associations, not effects.
Further findings
Independent factors associated with poor prognosis
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Male gender | 2.74 (1.22–6.14) | P = 0.014 | |
| Femoral cannulation siteAssociated with favorable outcome | 0.18 (0.06–0.52) | P = 0.002 | |
| 0.050.21520Adjusted odds ratio (log scale) |
| Outcome | aOR (per mol/L) (95% CI) | P value | |
|---|---|---|---|
| Independent factors associated with poor prognosisHigher serum lactate 24 h after CA | 1.11 (1.03–1.18) | P = 0.003 | |
| 0.512Adjusted odds ratio (log scale) |
Patient characteristics
- Cases per centre (median, range 0-21)
- 6
- Intra-hospital cardiac arrest (CA)
- 150, 91.5%
- Suspected cardiac origin
- 134 (84.3%)
- Preexistent cardiac disease
- 94 patients (57.3%)
Original publication
Characteristics and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (E-CPR): a nationwide retrospective analysis from the French pediatric ECMO Network. Ann Intensive Care. Published 25 July 2026. doi:10. 1016/ j. aicoj. 2026. 100126
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