Paediatric anaesthesia & critical care

Characteristics and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (E-CPR): a nationwide retrospective analysis from the French pediatric ECMO Network

Ann Intensive CarePublished Retrospective cohort study

Authors' conclusion

E-CPR is mostly performed in children with heart disease, with limited use in out-of-hospital settings.

Study context

Population
Children (0–18 years) undergoing ECPR for intra- or extra-hospital refractory cardiac arrest, French pediatric ECMO network, 2019–2023
Participants
164 children
Outcome
Incidence and outcomes of ECPR (survival)
Methodological detailsnationwide, multicentre network
  • Nationwide
  • Multicentre network

Main finding

As reported in the abstract

Survival

Survival at PICU discharge

29.9%

Survival at hospital discharge

29.3%

Survival after one year

27.4%

Observational data: associations, not effects.

Further findings

Independent factors associated with poor prognosis

aOR (95% CI)P value
Male gender2.74 (1.22–6.14)P = 0.014
Femoral cannulation siteAssociated with favorable outcome0.18 (0.06–0.52)P = 0.002
OutcomeaOR (per mol/L) (95% CI)P value
Independent factors associated with poor prognosisHigher serum lactate 24 h after CA1.11 (1.03–1.18)P = 0.003

Patient characteristics

Cases per centre (median, range 0-21)
6
Intra-hospital cardiac arrest (CA)
150, 91.5%
Suspected cardiac origin
134 (84.3%)
Preexistent cardiac disease
94 patients (57.3%)

Original publication

Characteristics and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (E-CPR): a nationwide retrospective analysis from the French pediatric ECMO Network. Ann Intensive Care. Published 25 July 2026. doi:10.1016/j.aicoj.2026.100126

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