ICU sedation, delirium & recovery
Characteristics and short-term outcomes of patients with hematological malignancies admitted to Intensive care units: a retrospective cohort study using the Japanese Intensive care PAtient Database
Authors' conclusion
In-hospital mortality of adult patients with hematological malignancies admitted to ICUs remains high. Factors associated with in-hospital mortality in these patients differed from those in the general ICU population. Institutional characteristics were not significantly associated with in-hospital mortality.
Study context
- Population
- Adults with hematological malignancies admitted to intensive care units (ICUs) participating in the Japanese Intensive care PAtient Database, 2015–2020
- Participants
- 1,700 adults · 69 institutions
- Exposure
- Survivors vs non-survivors
- Outcome
- In-hospital mortality
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
In-hospital mortality
46.2%
Observational data: associations, not effects.
Further findings
Predictors of in-hospital mortality (multivariable logistic regression)
| OR (95% CI) | ||
|---|---|---|
| Invasive mechanical ventilation | 1.64 (1.30–2.08) | |
| NIV | 1.71 (1.22–2.41) | |
| CRRT | 1.98 (1.51–2.61) | |
| 0.20.5125Odds ratio (log scale) |
- Type of neoplasm and APACHE III score independently associated with higher mortality
- Age, comorbidities, ICU admission source, reason for ICU admission not associated
- No association between institutional characteristics and in-hospital mortality
ICU admission reason and treatments
- Respiratory failure as most common reason for ICU admission
- 28.2%
- Mechanical ventilation used
- 49.0%
- CRRT used
- 24.6%
Original publication
Characteristics and short-term outcomes of patients with hematological malignancies admitted to Intensive care units: a retrospective cohort study using the Japanese Intensive care PAtient Database. Anaesth Crit Care Pain Med. Published 30 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →