Cardiac arrest & resuscitation
Characterizing the impact of thermoregulation in patients after cardiac arrest: a retrospective cohort study
Main finding · In-hospital deathResult — go to the resultOdds ratio 2.9 95% CI 1.9–4.2Authors' conclusion
In this single-centre retrospective cohort study, low spontaneous core body temperature was associated with poor outcomes in patients after cardiac arrest. Patients with low spontaneous body temperature also exhibited features suggestive of impaired thermoregulation.
Study context
- Population
- Adults who underwent temperature control with hypothermia after in- or out-of-hospital cardiac arrest, 1 January 2014 to 30 June 2020IHCA and OHCA
- Participants
- 597 adults
- Exposure
- Low spontaneous body temperature vs Higher spontaneous body temperature
- Outcome
- In-hospital death
Methodological detailssingle-centre, multivariable logistic regression
- Single-centre
- Multivariable logistic regression
Main finding
As reported in the abstract
Odds ratio
2.9
95% CI 1.9–4.2
P < 0.001
Low spontaneous body temperature vs Higher spontaneous body temperature
OR 2.9 (95% CI 1.9–4.2); P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Temperature profile in the first 24 hr
- Low spontaneous body temperature: slightly lower average temperature and more frequent transient but controlled breakthrough fever episodes
Original publication
Characterizing the impact of thermoregulation in patients after cardiac arrest: a retrospective cohort study. Can J Anaesth. Published 21 March 2024. doi:10.
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