Pediatric anesthesia & critical care

Child Opportunity Index and Pediatric Extracorporeal Membrane Oxygenation Outcomes; the Role of Diagnostic Category

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

SDoH are statistically associated with pediatric ECMO outcomes; however, associations differ between diagnostic categories. Influence of COI was observed only in cardiac patients while payer, race, and ethnicity results varied.

Study context

Population
Children (< 18 yr) supported on extracorporeal membrane oxygenation (ECMO), 44 US children's hospitals, October 1, 2015 to March 1, 2021; children without Child Opportunity Index (COI) excluded44 US children's hospitals
Participants
8,710 participants
Exposure
Social determinants of health (COI, race, ethnicity, payer, US region) and in-hospital mortality, by diagnostic category
Outcome
In-hospital mortality
Methodological detailsmulticentre, administrative database (Pediatric Health Information System)
  • Multicentre
  • Administrative database (Pediatric Health Information System)

Main finding

As reported in the abstract

Adjusted odds ratio (95% CI)
Pediatric cardiac: Hispanic ethnicityhigher survival
0.72(0.57–0.89)
Sepsis: Black race
1.62(1.06–2.47)
Pediatric respiratory: other payer
1.94(1.23–3.06)
Pediatric cardiac: every 10-point decrement in COI · multivariable logistic regression
odds of death 5% increased (95% CI 1.01–1.09)
Overall in-hospital mortality
33% (2863/8710)

Observational data: associations, not effects.

Further findings

Cardiac-surgical complexity and cannulation timing (heart disease, highest COI quintile)

Highest COI quintile had less cardiac-surgical complexity and earlier cannulation

Original publication

Child Opportunity Index and Pediatric Extracorporeal Membrane Oxygenation Outcomes; the Role of Diagnostic Category. Crit Care Med. Published 26 June 2024. doi:10.1097/ccm.0000000000006358

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