Pediatric anesthesia & critical care
Choice of creep or maintenance fluid type and their impact on total daily intensive care unit (ICU) sodium burden in critically ill patients: A systematic review and meta-analysis
Pooled result · Mean daily sodium reductionResult — go to the resultMean daily sodium reduction 117 mmol 95% CI −174 to −59Authors' conclusion
Using low sodium content maintenance/creep fluids substantially reduces daily sodium burden in adult ICU patients.
Study context
- Population
- Adult ICU patients (trials on resuscitation fluids, ED-only and pediatric excluded)
- Participants
- 1,105 patients · 5 studies
- Comparison
- Low vs high sodium content maintenance/creep fluids
- Outcome
- Reduction in mean total sodium intake
Pooled result
Mean daily sodium reduction
Mean daily sodium reduction
117 mmol
95% CI −174 to −59
P < 0.001
As reported in the abstract
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Hyperchloremia | 0.26 (0.1–0.64) | |
| 0.10.31310Odds ratio (log scale) |
Hyper-/hyponatremia and fluid balances
- No differences in incidences of hyper-/hyponatremia and fluid balances
Original publication
Choice of creep or maintenance fluid type and their impact on total daily ICU sodium burden in critically ill patients: A systematic review and meta-analysis. J Crit Care. Published 29 August 2023. doi:10. 1016/ j. jcrc. 2023. 154403
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