Chronic pain patients and time to sustained acceptable pain scores after major surgery - A retrospective registry analysis
Authors' conclusion
Patients with chronic pain sustain more surgical pain than those without, and the pain takes longer to resolve.
Study context
- Population
- Patients recovering from major surgery cared for by an acute pain service, German Network for Safety in Regional Anaesthesia and Acute Pain Therapy registry3.3% of treatments chronic pain
- Participants
- 107,412 patients
- Exposure
- Chronic pain vs no chronic pain
- Outcome
- Time to sustained acceptable pain at rest
Methodological detailsregistry analysis, adjusted Cox proportional hazard regression, propensity score matching sensitivity analysis
- Registry analysis
- Adjusted Cox proportional hazard regression
- Propensity score matching sensitivity analysis
Main finding
As reported in the abstract
Chronic pain vs No chronic painEstimate (95% CI)P value
Pain took significantly longer to resolve with chronic pain
aHR for longer time to resolution of pain at rest 1.42(1.36–1.49)
P < 0.001Pain with movement took even longer to resolve with chronic pain
aHR for longer time to resolution of pain with movement 1.65(1.56–1.75)
P < 0.001Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Chronic pain patients and time to sustained acceptable pain scores after major surgery - A retrospective registry analysis. J Clin Anesth. Published 25 May 2023. doi:10.
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