Neuroanesthesia & neurocritical care
Clinical characteristics and outcomes of critically ill adult patients admitted with traumatic brain injury: a cohort study
Authors' conclusion
Patients with traumatic brain injury have a high risk of in-hospital death. Those who survive the initial hospitalization are at risk of long-term outcomes including new epilepsy.
Study context
- Population
- Adults admitted to ICU with a first episode of TBI, Ontario, April 2009 to March 2021
- Participants
- 13,283 TBI patients
- Exposure
- TBI vs Trauma without TBI
- TBIn = 13,283
- Outcome
- In-hospital and long-term all-cause mortality
Methodological detailsmatched 1:1 comparison cohort
- Matched 1:1 comparison cohort
Main finding
As reported in the abstract
All-cause mortality (TBI cohort) · median follow-up 5 years
In-hospital death
17%
Death during long-term follow-up
16%
Observational data: associations, not effects.
Further findings
Other outcomes in TBI survivors vs survivors without TBI
- Risk of other outcomes similar or lower vs survivors without TBI
Long-term outcomes, TBI cohort (single-group) · median follow-up 5 years
- Death during long-term follow-up
- 16%
- Sepsis after hospital discharge
- 14%
- New psychiatric diagnosis
- 7%
- Epilepsy
- 4%
- Venous thromboembolic disease
- 2%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Clinical characteristics and outcomes of critically ill adult patients admitted with traumatic brain injury: a cohort study. Can J Anaesth. Published 22 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →