Cardiac arrest & resuscitation
Clinical characteristics and outcomes after extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients with an initial asystole rhythm
Authors' conclusion
A total of 202 ECPR cases with an initial asystole rhythm, including 12 patients with favourable neurological outcomes, were described.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) patients with an initial asystole rhythm treated with extracorporeal cardiopulmonary resuscitation (ECPR)
- Participants
- 202 patients
- Primary endpoint
- Favourable neurological outcome (cerebral performance categories 1-2)
- Follow-up
- Hospital discharge
Methodological detailsretrospective, multicentre, 36 institutions in Japan
- Retrospective
- Multicentre
- 36 institutions in Japan
Primary result
As reported in the abstract
Favourable neurological outcome at hospital discharge
Favourable neurological outcome, n (%)
12
5.9%
Further findings
Causes of arrest among patients with favourable neurological outcome
- Hypothermia
- 7
- ACS
- 2
- Arrhythmia
- 2
- PE
- 1
Non-hypothermia (≥32 °C) with asystole or pulseless electrical activity (PEA) on arrival lacking ≥1 requirement (witness; bystander CPR; signs of life or pupil < 5 mm)
- Patients lacking ≥1 requirement, all with unfavourable neurological outcome
- 107
- Asystole on arrival
- 66
- PEA on arrival
- 41
- Favourable-outcome cases meeting all requirements on arrival, except 1 with suspected short no-flow time
- 5
Original publication
Clinical characteristics and outcomes after extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients with an initial asystole rhythm. Resuscitation. Published 13 January 2023. doi:10.
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