Cardiac arrest & resuscitation

Heart rhythm at hospital admission: A factor for survival and neurological outcome among extracorporeal cardiopulmonary resuscitation (ECPR) recipients?

ResuscitationPublished Observational cohort study

Authors' conclusion

The rhythm at hospital admission affects ECPR outcomes. Patients presenting with and maintaining ventricular fibrillation have a higher chance of favorable neurological survival, whereas those presenting with or converting to asystole have poor outcomes.

Study context

Population
Patients who underwent ECPR for out-of-hospital cardiac arrest (OHCA), January 2012–December 2023196 analysed
Participants
210 patients
Exposure
Rhythm at hospital admission in ECPR recipients
  • VF/VFn = 67
  • Asystole/asystolen = 17
Outcome
30-day survival and neurological outcome
Follow-up
30 days; neurological outcome at discharge
Methodological detailssingle-centre, Median time to ECPR initiation 61 min (IQR 54-72)
  • Single-centre
  • Median time to ECPR initiation 61 min (IQR 54-72)

Main finding

As reported in the abstract

30-day survival · 30 days
Asystole at admissionOdds ratio (95 % CI)P value
30-day mortality; adjusted for age, sex, initial rhythm, resuscitation time, location, bystander, witnessed status
4.03(1.49–12.38)
P = 0.009
Worse neurological outcome (CPC 3-5) at discharge; adjusted
4.61(1.49–17.62)
P = 0.013
Survival across rhythm groups (log-rank)
P < 0.00001

Observational data: associations, not effects.

Original publication

Heart rhythm at hospital admission: A factor for survival and neurological outcome among ECPR recipients? Resuscitation. Published 16 October 2024. doi:10.1016/j.resuscitation.2024.110412

Composed by AI from the published abstract and checked against it. How Briefs are made →

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