Obstetric anesthesia

Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae

Perioper Med (Lond)Published Prospective comparative study

Authors' conclusion

0.1% ropivacaine combined with 0.5 μg/ml sufentanil through DPE technique has good analgesic efficacy and few adverse effects in obese puerperae.

Study context

Population
First-term obese women with vaginal delivery requiring labor analgesia
Participants
150 women
Exposure
A vs B vs C
Outcome
Analgesia characteristics
Methodological detailsthree groups
  • Three groups

Main finding

As reported in the abstract

  • Analgesia onset time, PCEA pressing time and ropivacaine consumption lower, analgesia time and first PCEA time longer in C than in A and B
  • Visual analog scale (VAS) scores higher in A than in B and C at T1-T3 and T5
  • Ramsay score lower in A than in B and C at T2-T3
  • Bromage score higher in C than the other two groups at any time point

Observational data: associations, not effects.

Further findings

Second stage of labor duration

Longer in B and C than in A; longer in C than in B

Maternal BP and heart rate

Closer to normal values in B than in A and C

Neonatal umbilical artery blood gas and Apgar scores at 1 and 5 min

No significant effect of the three concentrations

Original publication

Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae. Perioper Med (Lond). Published 15 February 2024. doi:10.1186/s13741-024-00363-1

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