Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae
Authors' conclusion
0.1% ropivacaine combined with 0.5 μg/ml sufentanil through DPE technique has good analgesic efficacy and few adverse effects in obese puerperae.
Study context
- Population
- First-term obese women with vaginal delivery requiring labor analgesia
- Participants
- 150 women
- Exposure
- A vs B vs C
- Outcome
- Analgesia characteristics
Methodological detailsthree groups
- Three groups
Main finding
As reported in the abstract
- Analgesia onset time, PCEA pressing time and ropivacaine consumption lower, analgesia time and first PCEA time longer in C than in A and B
- Visual analog scale (VAS) scores higher in A than in B and C at T1-T3 and T5
- Ramsay score lower in A than in B and C at T2-T3
- Bromage score higher in C than the other two groups at any time point
Observational data: associations, not effects.
Further findings
Second stage of labor duration
- Longer in B and C than in A; longer in C than in B
Maternal BP and heart rate
- Closer to normal values in B than in A and C
Neonatal umbilical artery blood gas and Apgar scores at 1 and 5 min
- No significant effect of the three concentrations
Original publication
Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae. Perioper Med (Lond). Published 15 February 2024. doi:10. 1186/ s13741-024-00363-1
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