Perioperative medicine & outcomes

The clinical effectiveness of preoperative screening and post-screening interventions for obstructive sleep apnea: A systematic review and meta-analysis

J Clin AnesthPublished Systematic review and meta-analysis

Authors' conclusion

Our findings confirm HR-OSA as a risk factor for postoperative adverse events.

Study context

Population
Surgical patients screened preoperatively for obstructive sleep apnea (OSA) with validated tools
Participants
324,935 patients · 54 studies
Comparison
High risk of OSA (HR-OSA) vs low risk of OSA (LR-OSA); post-screening interventions vs no intervention in HR-OSA
Outcome
Postoperative adverse respiratory and cardiac events, delirium, length of stay (LOS), ICU admissions, 30-day readmissions, and mortality

Pooled result

As reported in the abstract

HR-OSA vs LR-OSA
HR-OSA vs LR-OSAOdds ratio (95 % CI)
Respiratory complications
3.59(1.73–7.43)
Cardiac complications
2.82(1.62–4.92)
HR-OSA vs LR-OSAMean difference, days (95 % CI)
Hospital LOS
0.79(0.42–1.15)

Further pooled results

OutcomeOR (95 % CI)
Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · respiratory complications0.86 (0.56–1.31)
Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · delirium0.69 (0.12–4.06)
Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · escalation of care0.86 (0.62–1.18)
Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · composite adverse events0.81 (0.61–1.08)

Post-screening interventions vs no intervention in HR-OSA

No significant differences

Original publication

The clinical effectiveness of preoperative screening and post-screening interventions for obstructive sleep apnea: A systematic review and meta-analysis. J Clin Anesth. Published 11 December 2025. doi:10.1016/j.jclinane.2025.112084

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