Perioperative medicine & outcomes
The clinical effectiveness of preoperative screening and post-screening interventions for obstructive sleep apnea: A systematic review and meta-analysis
Authors' conclusion
Our findings confirm HR-OSA as a risk factor for postoperative adverse events.
Study context
- Population
- Surgical patients screened preoperatively for obstructive sleep apnea (OSA) with validated tools
- Participants
- 324,935 patients · 54 studies
- Comparison
- High risk of OSA (HR-OSA) vs low risk of OSA (LR-OSA); post-screening interventions vs no intervention in HR-OSA
- Outcome
- Postoperative adverse respiratory and cardiac events, delirium, length of stay (LOS), ICU admissions, 30-day readmissions, and mortality
Pooled result
As reported in the abstract
HR-OSA vs LR-OSA
HR-OSA vs LR-OSAOdds ratio (95 % CI)
Respiratory complications
3.59(1.73–7.43)
Cardiac complications
2.82(1.62–4.92)
HR-OSA vs LR-OSAMean difference, days (95 % CI)
Hospital LOS
0.79(0.42–1.15)
Further pooled results
| Outcome | OR (95 % CI) | |
|---|---|---|
| Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · respiratory complications | 0.86 (0.56–1.31) | |
| Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · delirium | 0.69 (0.12–4.06) | |
| Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · escalation of care | 0.86 (0.62–1.18) | |
| Post-screening interventions vs no intervention in HR-OSAIntervention vs No intervention · composite adverse events | 0.81 (0.61–1.08) | |
| 0.10.31310Odds ratio (log scale) |
Post-screening interventions vs no intervention in HR-OSA
- No significant differences
Original publication
The clinical effectiveness of preoperative screening and post-screening interventions for obstructive sleep apnea: A systematic review and meta-analysis. J Clin Anesth. Published 11 December 2025. doi:10. 1016/ j. jclinane. 2025. 112084
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