Clinical outcomes of dengue patients requiring intensive care in Brazil: A 10-year nationwide observational study
Authors' conclusion
Dengue requiring ICU admission in Brazil is associated with significant morbimortality. Mortality rates were higher in subgroups such as old patients and those admitted to public hospitals.
Study context
- Population
- Adult dengue intensive care unit (ICU) admissions in Brazil, 2015–2024admission episodes
- Participants
- 32,016 vs 11,241
- Exposure
- ICU registry vs DATASUS
- ICU registryn = 32,016
- DATASUSn = 11,241
- Outcome
- ICU and in-hospital mortality, organ support, and LOS
Methodological detailsnationwide, two complementary datasets
- Nationwide
- Two complementary datasets
Main finding
As reported in the abstract
In-hospital mortality
Observational data: associations, not effects.
Further findings
- Organ support in first 24 h of ICU (ICU registry)
- 5.8% · mechanical ventilation · vasopressors 7.2%
- Mortality, public hospitals (ICU registry subgroup)
- 20% · ICU mortality · in-hospital mortality 25%
Mortality in subgroups (older patients, vasopressor use)
- Unadjusted mortality rates higher in older patients and those using vasopressors
Original publication
Clinical outcomes of dengue patients requiring intensive care in Brazil: A 10-year nationwide observational study. J Crit Care. Published 28 August 2026. doi:10.
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