Airway management

Clinical tests for confirming tracheal intubation or excluding oesophageal intubation: a diagnostic test accuracy systematic review and meta‐analysis

AnaesthesiaPublished Diagnostic test accuracy systematic review and meta-analysis

Authors' conclusion

Misting or auscultation have too high a false positive rate to reliably exclude oesophageal intubation and there is insufficient evidence to support the use of 'hang-up' or chest rise.

Study context

Population
Patients undergoing tracheal intubation; index clinical tests vs reference standard (capnography, direct vision, bronchoscopy)
Participants
10,654 patients · 49 studies
Comparison
Clinical examination tests and the oesophageal detector device vs reference standard for confirming tracheal intubation
  • Mistingn = 115
  • Lung auscultationn = 217
  • Five-point auscultationn = 506
  • Oesophageal detector devicen = 3,024
Outcome
Diagnostic accuracy (false positive rate) for confirming tracheal intubation
Methodological detailsMethodological quality overall moderate to high, Four databases searched to 28 February 2023, Reference standards: capnography (22 studies), direct vision (10), bronchoscopy (3)
  • Methodological quality overall moderate to high
  • Four databases searched to 28 February 2023
  • Reference standards: capnography (22 studies), direct vision (10), bronchoscopy (3)

Pooled result

As reported in the abstract

False positive rate for confirming tracheal intubation
GroupFalse positive rate (95%CI)
Misting0.69 (0.43-0.87)
Lung auscultation0.14 (0.08-0.23)
Five-point auscultation0.18 (0.08-0.36)
Oesophageal detector device0.05 (0.02-0.09)

False positive rate (95%CI)

Misting0.69 (0.43-0.87)
Lung auscultation0.14 (0.08-0.23)
Five-point auscultation0.18 (0.08-0.36)
Oesophageal detector device0.05 (0.02-0.09)

Original publication

Clinical tests for confirming tracheal intubation or excluding oesophageal intubation: a diagnostic test accuracy systematic review and meta‐analysis. Anaesthesia. Published 16 June 2023. doi:10.1111/anae.16059

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